MK-0557

CAT: 0026-B2317-25Size: 25 mgDry Ice: NoHazardous: No
CAT#:0026-B2317-25Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent and selective antagonist of the neuropeptide Y (NPY) receptor Y5. It is >7,500-fold selective for Y5 over other receptors and lacks activity in a panel of 180 receptors, enzymes, and ion channels at concentrations up to 1 μM. In vivo, MK-0557 (30 mg/kg) reduces body weight gain in wild-type and diet-induced obese mice. It also reduces retroperitoneal fat pad weight, epididymal and mesenteric fat pad weights, leptin levels, and food intake in lean mice fed a high-fat diet.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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