N-Acetyl-4-benzoquinone Imine

CAT:

26-B2306-5

Size:

5 mg

Price:

Ask

For price, please contact [email protected]

Description: N-Acetyl-4-benzoquinone Imine (NAPQI) is a toxic cytochrome P450 3A4 and 2E1 metabolite of Acetaminophen. At therapeutic doses of acetaminophen, NAPQI is inactivated by conjugation with glutathione. However, following toxic doses of acetaminophen, available liver reserves of glutathione are quickly depleted due to clearance of excess NAPQI, which enables hepatic proteins to become covalently modified by reactive metabolites and eventually results in hepatocyte necrosis.
Shipping Conditions: gel pack
Storage Conditions: -20°C
Shelf Life: 36 months

Cat	Name
B2306-5	N-Acetyl-4-benzoquinone Imine
B2306-1	N-Acetyl-4-benzoquinone Imine
B1813-1G	N-Acetyl-L-cysteine
B1813-5G	N-Acetyl-L-cysteine
B1803-1000	5-Bromo-4-chloro-3-indoxyl-N-acetyl-beta-D-glucosaminide
B1803-250	5-Bromo-4-chloro-3-indoxyl-N-acetyl-beta-D-glucosaminide
6781-50	N-Cadherin Antibody (Clone # EPR1791-4)
A1029-100	Acetyl-Lysine Monoclonal Antibody
3653-100	Acetyl-Histone H2A Antibody
3654-100	Acetyl-Histone H2B Antibody