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IACS-010759

CAT: 0026-B2231-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2231-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IACS-010759 is a potent and selective Oxidative Phosphorylation Inhibitor (IC₅₀ < 10 nM) with potential antineoplastic activity. IACS-010759 robustly inhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS, likely owing to a combination of energy depletion and reduced aspartate production that leads to impaired nucleotide biosynthesis.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months