LOXO-195

CAT: 0026-B2226-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B2226-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LOXO-195 is a potent and selective TRK (tropomyosin-related-kinase) inhibitor, with potential anticancer activity. LOXO-195 specifically targets and binds to TRK, including the fusion proteins containing sequences from neurotrophic tyrosine receptor kinase (NTRK) types 1 (NTRK1), 2 (NTRK2), and 3 (NTRK3). This prevents neurotrophin-TRK interaction and TRK activation, which results in both the induction of cellular apoptosis and the inhibition of cell growth in tumors that overexpress TRK and/or express NTRK fusion proteins.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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