Products for Research Use Only

AT7867

CAT: 0026-B2178-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2178-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AT7867 is a potent inhibitor of Akt isoforms Akt1, 2, and 3 (IC₅₀s = 32, 17, and 47 nM, respectively). It also inhibits p70S6 kinase and PKA (IC₅₀s = 85 and 20 nM, respectively), but is without effect against a panel of other kinases. AT7867 inhibits growth and induces apoptosis in a variety of cancer cell lines in vitro and suppresses tumor growth of PTEN-deficient xenografts in mice.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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