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RWJ-67657

CAT: 0026-B2098-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B2098-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RWJ-67657 is a potent inhibitor of the MAP kinases p38α and p38β (IC₅₀s = 1 and 11 µM, respectively, in vitro); inactive against p38γ and p38δ, as well as several other kinases. RWJ-67657 blocks the release of TNF-α and IL-1β from peripheral blood mononuclear cells stimulated with LPS (IC₅₀s = 3 and 11 nM, respectively) and inhibits TNF-α production in LPS-treated mice and rats.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months