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Vincristine sulfate

CAT: 0026-B2048-10Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0026-B2048-10Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vincristine is a plant alkaloid isolated from Vinca Rosea that irreversibly blocks mitosis by binding to tubulin (Ki = 85 nM) and inhibiting tubulin polymerization. It arrests cell cycle in G2/M-phase by blocking mitotic spindle formation. Vincristine is exported from cells via the ATP-binding cassette transporter P-glycoprotein, but not by multidrug resistance-associated protein.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months