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TPX-0005

CAT: 0026-B2027-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B2027-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TPX-0005 is a potent ALK inhibitor. It inhibits WT ALK (IC50 1.01 nM) and mutant ALKs including ALK G1202R (IC₅₀ = 1.26 nM) and ALK L1196M (IC₅₀ = 1.08 nM). Moreover, TPX-0005 effectively inhibits tumor growth in vivo in ALK WT and ALK G1202R xenografts. TPX-0005 is also a potent SRC inhibitor (IC₅₀ = 5.3 nM).
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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