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MK-0752

CAT: 0026-B1980-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B1980-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MK-0752 is a potent and reversible inhibitor of γ-secretase, reducing the cleavage of APP to Aβ40 in human neuroblastoma SH-SY5Y cells (IC₅₀ = 5 nM). Through its effects on the Notch pathway, MK-0752 reduces the number of breast cancer stem cells in tumorgrafts, enhancing the efficacy of the chemotherapy drug docetaxel (Cat. No. 2232) in mice with breast cancer tumors.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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