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MAK-683

CAT: 0026-B1972-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B1972-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MAK-683 is a potent EED (embryonic ectoderm development protein) inhibitor and an allosteric inhibitor of polycomb repressive complex 2 (PRC2), with potential antineoplastic activity. MAK683 selectively binds to the domain of EED that interacts with trimethylated lysine 27 on histone 3 (H3K27me3), which leads to a conformational change in the EED H3K27me3-binding pocket and prevents the interaction of EED with the histone methyltransferase enhancer zeste homolog 2 (EZH2).
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

Alternative Products

CatalogName
BDD40858-01MAK-683
T9681-01MAK-683 hydrochloride
MBS5786490MAK-683 hyrochloride
A16922-100MAK-683 100mg
A16922-50MAK-683 50mg
A16922-25MAK-683 25mg
A16922-10MAK-683 10mg
A16922-5MAK-683 5mg
A16922-1MAK-683 1mg
A16922-500MAK-683 500mg

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