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Serabelisib

CAT: 0026-B1930-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B1930-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Serabelisib is a potent inhibitor of phosphoinositide 3-kinase α (PI3Kα) that is selective for p110α in vitro (IC₅₀ = 15 nM for PI3Kα vs. >1 µM for other isoforms, as well as for mTOR). MLN1117 inhibits AKT phosphorylation and growth in PIK3CA mutant breast cancer cells with IC₅₀ values around 2 μM, yet has no effect on cells lacking PTEN.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months