LY-2784544

CAT: 0026-B1914-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B1914-5Size:5 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LY2784544 is a potent, selective and ATP-competitive JAK2 inhibitor (IC₅₀ = 3 nM). effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. LY2784544 effectively inhibits JAK2V617F-driven signaling and cell proliferation in Ba/F3 cells (IC₅₀= 20 and 55 nM, respectively). In comparison, LY2784544 is much less potent at inhibiting interleukin-3-stimulated wild-type JAK2-mediated signaling and cell proliferation (IC₅₀ = 1183 and 1309 nM, respectively).
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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