EML-425

CAT: 0026-B1882-25Size: 25 mgDry Ice: NoHazardous: No
CAT#:0026-B1882-25Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EML-425 is a potent, reversible and non-competitive dual CBP and p300 inhibitor (IC₅₀ values are 1.1 and 2.9 μM, respectively).  EML425 induced a marked and time-dependent reduction in the acetylation of lysine H4K5 and H3K9, a marked arrest in the G0/G1 phase and a significant increase in the hypodiploid nuclei percentage in human leukemia U937 cells. Cell-permeable.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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