BAY 87-2243

CAT: 0026-B1878-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B1878-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced gene activation. It inhibits HIF-1α and HIF-2α protein accumulation under hypoxic conditions in non-small cell lung cancer (NSCLC) cell line H460 but had no effect on HIF-1α protein levels induced by the hypoxia mimetics desferrioxamine or cobalt chloride. In addition, BAY 87-2243 is also found to act as an inhibitor of mitochondrial function. It can inhibit the oxygen consumption with IC₅₀ value of 10 nM.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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Alternative Products

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205901BAY 87-2243
A12978-10BAY 87-2243 10mg
A12978-25BAY 87-2243 25mg
A12978-2BAY 87-2243 2mg
A12978-100BAY 87-2243 100mg
A12978-5BAY 87-2243 5mg
A12978-50BAY 87-2243 50mg
442157-01BAY 87-2243-d8
A12978-10mM-DBAY 87-2243 10mM * 1mL in DMSO
TBI4910-25MGBAY 87-2243, HIF-1 / Mitochondrial complex I inhibitor

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