RI-1

CAT: 0026-B1823-25Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0026-B1823-25Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

RI-1 is a potent and selective inhibitor of RAD51 (IC₅₀ = 5-30 μM). It specifically reduces gene conversion in human cells and stimulates single strand annealing. It covalently binds to Cys319 on the surface of RAD51 and disrupts protein-protein interaction. It potentiates the effect of DNA-damaging agents on tumor cells and is a novel tool for studying DNA repair in cells. Potentiates the killing of glioblastoma cells by ionizing radiation and alkylating drugs.

Shipping Conditions

Gel Pack

Storage Conditions

-20°C

Shelf Life

36 months

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RI-1

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