SM-164

CAT: 0026-B1816-1000Size: 1 mgDry Ice: NoHazardous: No
CAT#:0026-B1816-1000Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SM-164 is a potent cell-permeable and bivalent Smac mimetic which binds to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 proteins with Ki values of 0.31 and 1.1 nM, respectively. It displays antitumor properties through inducing degradation of cellular inhibitor of apoptosis protein (cIAP)-1/2, antagonizing X-linked inhibitor of apoptosis protein (XIAP) and inducing TNFα–dependent apoptosis in tumor cells.
Shipping Conditions
Gel Pack
Storage Conditions
-20°C
Shelf Life
36 months

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