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NSC-663284

CAT: 0026-B1809-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B1809-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NSC-663284 is a potent, selective and irreversible inhibitor of all Cdc25 isoforms, with preference for Cdc25A (IC₅₀ = 29, 95, and 89 nM for Cdc25A, Cdc25B2, and Cdc25C, respectively). Displays > 20- and > 450-fold selectivity over VHR and PTP1B phosphatases respectively. Arrests cells at both G1 and G2/M phase and blocks cdk2 and cdk1 activation. Blocks proliferation of a range of human tumor cell lines (IC₅₀ = 0.2 - 35 μM).
Shipping Conditions
Gel Pack
Storage Conditions
-20°C
Shelf Life
36 months

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Alternative Products

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MBS808217-01NSC 663284
MBS516356-01NSC-663284
HY-100034RNSC 663284 (Standard)
A13524-25NSC 663284 25mg

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