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Ryuvidine

CAT: 0026-B1808-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B1808-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ryuvidine is a potent inhibitor of SET domain-containing protein 8 (SETD8) (IC₅₀ = 0.5 µM) that suppresses monomethylation of H4K20 in vitro. It displays weak inhibiton against cyclin-dependent kinase 4 (Cdk4; IC₅₀ = 6 µM for Cdk4/cyclin D1). Induces S phase accumulation in HEK293T cells. Cytotoxic against a range of human cancer cells.
Shipping Conditions
Gel Pack
Storage Conditions
-20°C
Shelf Life
36 months