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AS-252424

CAT: 0026-B1611-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B1611-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AS-252424 is a potent inhibitor of PI3K with selectivity for the γ isoform. It inhibits human recombinant PI3Kγ IC50= 30 nM, PI3Ka IC50=940 nM, PI3Kb IC50=20,000 nM and PI3Kd IC50= 20,000 nM respectively. AS-252424 also inhibits C5a-mediated phosphorylation of Akt in RAW 264.7 macrophages with an IC50=230 nM. In a mouse model of peritonitis, PI 3-Kᵧ this compound inhibited neutrophil recruitment 35% at a dose of 10 mg/kg.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

Alternative Products

CatalogName
B2180-25AS-252424
FA101250-01AS 252424

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