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DSG3 Antibody / Desmoglein 3

CAT: 0013-GTR18574892Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18574892Size:100 µg
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Description
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. [UniProt]
UniProt
P32926
Reactivity
Human
Immunogen
Amino acids 379-491 were used as the immunogen for the DSG3 antibody.
Clonality
Monoclonal
Clone
CFM6-1
Conjugation
Unconjugated
Purification
Protein G affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
The stated application concentrations are suggested starting points. Titration of the DSG3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

UniProtKB · P32926

Desmoglein-3

DSG3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P32926
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DSG3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A8K2V2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

CalciumMetal-binding

Biological process

Cell adhesion

Cellular component

Cell junctionCell membraneCytoplasmMembraneTight junction

PTM

Cleavage on pair of basic residuesGlycoprotein

Domain

RepeatSignalTransmembraneTransmembrane helix

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