Products for Research Use Only

Novobiocin Sodium Salt

CAT: 0026-B1526-1GSize: 1 gDry Ice: NoHazardous: No
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CAT#:0026-B1526-1GSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Novobiocin is a coumarin antibiotic isolated from Streptomyces species, that inhibits the ATPase activity of DNA gyrase. Its antibacterial activity arises from competitive inhibition of the ATPase reaction catalyzed by the GyrB subunit. In addition to permitting relaxation of negative supercoils, novobiocin has been used to generate positively supercoiled DNA. It has also been shown to inhibit the chaperone activity of Hsp90 as well as acting as an inhibitor of DNA Topoisomerase II.
Shipping Conditions
Gel Pack
Storage Conditions
+4°C
Shelf Life
36 months