Products for Research Use Only

Alpelisib

CAT: 0026-B1271-5Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0026-B1271-5Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Alpelisib (also known as BYL719), is a potent and selective phosphatidylinositol-3 kinase α inhibitor. It inhibits P110α, p110β, p110δ, and p110g with IC₅₀ values of 5 nM, 1.2 µM, 0.29 µM and 0.25 µM, respectively, in biochemical assays. It inhibits the Akt phosphorylation with IC₅₀ values of 74 nM in Rat1-myr-p110α cells, 2.2 µM in Rat1-myr-p110β cells, and 1.2 µM in Rat1-myr-p110δ cells.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months