UNC-2025

• Description:

  UNC-2025 is a potent inhibitor of the tyrosine kinases Mer and Flt3 (IC₅₀s = 0.74 and 0.80 nM, respectively). It less potently inhibits Axl and Tyro3 (IC₅₀s = 14 and 17 nM, respectively) and a panel of related kinases. UNC2025 blocks colony formation of Mer- and Flt3-dependent tumor cell lines and inhibits Mer phosphorylation in bone marrow leukemia cells in vivo.

• Shipping Conditions:

  gel pack

• Storage Conditions:

  -20°C

• Shelf Life:

  36 months