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ABC294640

CAT: 0026-B1231-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B1231-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ABC294640 is a specific spingosine kinase-2 (SK-2) inhibitor having antineoplastic activity. This orally available aryl admantane molecule upon administration binds and inhibits SK-2, preventing phosphorylation of the pro-apoptotic amino alcohol spingosine to spingosine-1-phosphate (S1P), the lipid mediator that is important for immunomodulation, this phosphorylation prevention of amino alcohol can induce apoptosis and may inhibit cancer cell proliferation.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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