CB-839

CAT: 0026-B1179-25Size: 25 mgDry Ice: NoHazardous: No
CAT#:0026-B1179-25Size:25 mg
Selected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
CB-839 is a potent, selective, and orally bioavailable inhibitor of both splice variants of glutaminase (KGA and GAC); inhibits recombinant GAC with an IC₅₀ of <15 nM. CB-839 displays antiproliferative activity in a triple-negative breast cancer (TNBC) cell line, HCC-1806, that is associated with a marked decrease in glutamine consumption, glutamate production, oxygen consumption, and the steady-state levels of glutathione and several tricarboxylic acid cycle intermediates.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

Popular Products