Products for Research Use Only

NKL 22 (MDK-4154)

CAT: 0026-B1133-50Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0026-B1133-50Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NKL 22 (also known as MDK-4154) is a cell-permeable compound that acts as a FXN- (frataxin gene) specific HDAC (histone deacetylase) inhibitor. It reverses the silencing of FXN transcription in FRDA (Friedreich’s ataxia) cells due to hypoacetylation of histones H3 and H4 by increasing acetylation at H3K14, H4K12, and H4K5 without much acetylation on H3K9, H4K8 and H4K16.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months