WDR5 0103

CAT: 0026-B1125-50Size: 50 mgDry Ice: NoHazardous: No
CAT#:0026-B1125-50Size:50 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WDR5-0103 is a small molecule that binds a peptide-binding pocket on WDR5 (Kd = 450 nM). It inhibits the catalytic activity of MLL core complex in in vitro experiments with IC₅₀ of 39 µM. WDR5 is a component of mixed lineage leukemia (MLL) that targets histone-3 and in vitro data shows interaction of WDR5-0103 with MLL inhibits MLL core complex methyltransferase activity. However WDR5-0103 has no effect on other methyltransferases.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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