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GSK137647A

CAT: 0026-B1112-50Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0026-B1112-50Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK137647A is a a selective agonist of FFA4 (GPR120) (pEC₅₀s = 6.3, 6.2, and 6.1 at human, mouse, and rat receptors, respectively). It is selective for GPR120 over a panel of 61 other targets, including other FFARs. Like the natural GPR120 ligand linoleic acid, GSK137647A dose-dependently stimulates insulin secretion by mouse insulinoma MIN6 cells under high glucose conditions. It also modestly stimulates the production of glucagon-like peptide-1 in taste bud cells and human intestinal NCI-H716 cells.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months