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UMI-77

CAT: 0026-B1108-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B1108-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UMI-77 is a novel, selective, Mcl-1 SMI inhibitor. UMI-77 is selective for Mcl-1 over other members of the antiapoptotic Bcl-2 family with a Ki of 490 nM. UMI-77 acts by binding to the BH3-binding groove of Mcl-1, blocking the heterodimerization of Mcl-1/Bax and Mcl-1/Bak. It inhibits cell growth and induces apoptosis in pancreatic cancer cells.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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