K858

• Description:

  K858 is a selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor (IC₅₀ = 1.3 µM) and an antitumor agent. Induces cell death in cancer cells, blocks centrosome separation, activates the spindle checkpoint, and induces mitotic arrest in cells accompanied by the formation of monopolar spindles.

• Shipping Conditions:

  gel pack

• Storage Conditions:

  -20°C

• Shelf Life:

  36 months