Orlistat

• Description:

  Orlistat is a cell-permeable, selective, and competitive lipase inhibitor (IC₅₀ = 0.15 µM). Targets serine hydrolases in the nervous system, such as diacylglycerol lipase (DAGL), which is responsible for the conversion of DAG to 2-AG. Partially inhibits the hydrolysis of triglycerides and lowers the absorption of dietary fat, promoting weight loss. Promotes the sensitivity to TRAIL in cancer cells by ROS-mediated pathways. Displays antiobesity and antihypercholesterolemic activity in vivo.

• Shipping Conditions:

  gel pack

• Storage Conditions:

  -20°C

• Shelf Life:

  36 months