L-189

CAT: 0026-9674-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-9674-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-189 is a DNA ligase I, III and IV inhibitor (IC₅₀ values are 5, 9 and 5 μM respectively) that blocks DNA binding (Ki= 5 μM for DNA ligase I). L-189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ). L-189 specifically sensitizes cancer cells to DNA damage and increases the cytotoxicity of DNA-damaging agents.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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