Products for Research Use Only

RQ-002303078

CAT: 0026-9636-50Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0026-9636-50Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RQ-00203078 is a potent, selective TRPM8 antagonist (IC₅₀ values are 5.3 and 8.3 nM for rat and human channels respectively). Displays >350-fold selectivity for TRPM8 over TRPV4, TRPV1 and TRPA1. RQ-00203078 blocks TRPM8 activity and reduces the invasion potential of oral squamous carcinoma cell lines. RQ-00203078 (RQ) profoundly reduced such agonist-induced cation currents.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months