U-104

CAT: 0026-9631-5Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0026-9631-5Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

U-104 is a ureido-sulfonamide inhibitor of transmembrane carbonic anhydrase IX (CAIX) (Ki = 45.1 nM) and XII (CAXII) (Ki = 4.5 nM). It displays weaker affinity for the cytosolic isoforms, CAI and CAII (Kis = 5.08 and 9.64 µM, respectively). U-104 associates with CAIX/CAXII only under hypoxic conditions in vivo, reducing extracellular acidity and resulting in significant inhibition of tumor growth and metastasis in experimental models.

Shipping Conditions

gel pack

Storage Conditions

-20°C

Shelf Life

36 months

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Alternative Products

Catalog	Name
A4358-25	U-104
256988-01	U 104
A14959-25	U-104 25mg
A14959-500	U-104 500mg
A14959-10	U-104 10mg
A14959-200	U-104 200mg

U-104

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