STF-118804

CAT: 0026-9552-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-9552-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
STF-118804 is a potent and highly specific inhibitor of Nampt (nicotinamide phosphoribosyl transferase) (IC₅₀s = 3-6 nM) that prevents NAD⁺ synthesis from nicotinamide. It inhibits the viability of multiple B-cell acute lymphoblastic leukemia (B-ALL) cell lines with nanomolar potency and induces apoptosis in MV411 cells. It improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia, and targets leukemia stem cells.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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