GW-6471

• Description :

  GW-6471 is a potent PPARα antagonist (IC₅₀ = 240 nM). It drives the displacement of coactivators from PPARα and promotes the recruitment of co-repressor proteins like nuclear co-repressor. GW-6471 significantly prevents cardiomyocyte differentiation and results in the reduced expression of cardiac sarcomeric proteins and specific genes in a time-dependent manner.

• Shipping Conditions :

  Gel pack

• Storage Conditions :

  -20°C

• Shelf Life :

  36 months