GW-6471

CAT:
26-9453-1
Size:
1 mg
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
GW-6471 - image 1

GW-6471

  • Description:

    GW-6471 is a potent PPARα antagonist (IC₅₀ = 240 nM). It drives the displacement of coactivators from PPARα and promotes the recruitment of co-repressor proteins like nuclear co-repressor. GW-6471 significantly prevents cardiomyocyte differentiation and results in the reduced expression of cardiac sarcomeric proteins and specific genes in a time-dependent manner.
  • Shipping Conditions:

    Gel pack
  • Storage Conditions:

    -20°C
  • Shelf Life:

    36 months