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URMC-099

CAT: 0026-9443-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-9443-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
URMC-099 is a brain-permeable, mixed lineage kinase (MLK) inhibitor with IC₅₀ values of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively. In vitro, URMC-099 treatment reduces inflammatory cytokine production by HIV-1 Tat-exposed microglia and prevents destruction and phagocytosis of cultured neuronal axons by these cells.
Shipping Conditions
Gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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