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ELR-510444

CAT: 0026-9433-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-9433-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ELR-510444 is a potent microtube disruptor with potential anticancer activity. It displays potent microtubule-disrupting activity, causing a loss of cellular microtubules and the formation of aberrant mitotic spindles and leading to mitotic arrest and apoptosis of cancer cells. ELR-510444 potently inhibits cell proliferation with an IC₅₀ value of 30.9 nM in MDA-MB-231 cells, inhibits the rate and extent of purified tubulin assembly, and displaces colchicine from tubulin, indicating that the drug directly interacts with tubulin at the colchicine-binding site.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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