Products for Research Use Only

SR1664

CAT: 0026-9432-1Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0026-9432-1Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SR1664 blocks phosphorylation of peroxisome proliferator-activated receptor γ (PPARγ) by cyclin-dependent kinase 5 with an IC₅₀ value of 80 nM (Ki = 28.7 nM) without displaying agonist activity at the PPARγ receptor. It demonstrates potent, dose-dependent anti-diabetic effects in obese mice without inducing fluid retention and weight gain or inhibiting bone formation.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months