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LH-846

CAT: 0026-9423-10Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0026-9423-10Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LH-846 is a potent and selective inhibitor of casein kinase (CK) 1δ (IC₅₀ values are 290 nM, 1.3 μM and 2.5 μM for CK1δ, ε andα); displays no inhibitory activity at CK2. Inhibits CK1δ-dependent phosphorylation and degradation of PER1 protein. LH846 increases circadian period by 10 hours in human U2OS cells.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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