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AZD-7762

CAT: 0026-9414-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-9414-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZD7762 is a potent, ATP-competitive, reversible, checkpoint kinase inhibitor with IC₅₀s at 5 nM and <10 nM for Chk1 and Chk2, respectively. AZD 7762 abrogates DNA damage-induced S and G2 checkpoints with an EC₅₀ value of 10 nM and potentiates the efficacy of DNA-damage repair prohibitive agents, gemcitabine and topotecan, both in vitro and in various tumor xenografts by modulating downstream checkpoint pathway proteins.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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