TDZD-8

CAT: 0026-2854-25Size: 25 mgDry Ice: NoHazardous: No
CAT#:0026-2854-25Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TDZD-8 is a non-ATP competitive inhibitor of the serine/threonine kinase glycogen synthase kinase 3β (GSK3β; IC₅₀ = 2 µM), binding to the active site of GSK3β. It does not significantly affect the activities of Cdk-1/cyclin B, CK-II, cAMP-dependent protein kinase, or protein kinase C (IC₅₀s = >100 µM). TDZD-8 also causes rapid death of leukemia stem and progenitor cells.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months