TDZD-8

TDZD-8

• Description: TDZD-8 is a non-ATP competitive inhibitor of the serine/threonine kinase glycogen synthase kinase 3β (GSK3β; IC₅₀ = 2 µM), binding to the active site of GSK3β. It does not significantly affect the activities of Cdk-1/cyclin B, CK-II, cAMP-dependent protein kinase, or protein kinase C (IC₅₀s = >100 µM). TDZD-8 also causes rapid death of leukemia stem and progenitor cells.
• Shipping Conditions: gel pack
• Storage Conditions: -20°C
• Shelf Life: 36 months