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TW-37

CAT: 0026-2789-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-2789-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TW-37 is a novel nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.29 μM, 1.11 μM and 0.26 μM, respectively.  TW-37 inhibits the growth of a broad range of cancer cells (such as breast, prostate, lymphoma, and pancreatic cancer), since it induces S-phase cell cycle arrest with regulation of several important cell cycle related genes, including p27, p57, E2F-1, cdc25A, CDK4, cyclin A, cyclin D1 and cyclin E.
Shipping Conditions
Gel Pack
Storage Conditions
-20°C
Shelf Life
36 months

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