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Picropodophyllotoxin

CAT: 0026-2765-1Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0026-2765-1Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF1R) which is non-competitive with ATP. Displays no activity at IR, EGFR, FGFR or PDGFR. Inhibits IGF1R autophosphorylation IC₅₀ ~ 1 nM. Displays antiproliferative activity in numerous tumor cell lines, IC₅₀ = 0.05 - 15 mM. Exhibits antiangiogenic activitiy.
Shipping Conditions
Gel Pack
Storage Conditions
-20°C
Shelf Life
36 months

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