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OTX015

CAT: 0026-2651-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-2651-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
OTX015 is a potent inhibitor of BRD2, BRD3, and BRD4 (EC₅₀s = 10-19 nM). It displays antiproliferative effects at a sub-micromolar range in vitro in a wide range of solid tumor types and leukemias, downregulating c-Myc expression and inducing cell cycle arrest and apoptosis. At 100 mg/kg, OTX015 has been shown to inhibit the growth of Ty82 BRD-NUT midline carcinoma tumors in nude mice by 79%.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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