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Stattic

CAT: 0026-2625-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-2625-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Stattic is a small molecule that selectively inhibits STAT3 activation, dimerization, and nuclear translocation by preventing the binding of tyrosine-phosphorylated peptide motifs to the STAT3 SH2 domain (IC₅₀ = 5.1 μM at 37°C). Displays selectivity over STAT1, STAT5, c-Myc/Max, Jun/Jun and Lck. At 10 μM, stattic induces apoptosis in STAT3-dependent breast cancer (MDA-MB-231 and MDA-MB-435S) cell lines.
Shipping Conditions
Gel pack
Storage Conditions
-20 ̊C
Shelf Life
36 months

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CatalogName
A2224-25Stattic

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