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Borrelidin

CAT: 0026-2367-250Size: 250 µgDry Ice: NoHazardous: No
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CAT#:0026-2367-250Size:250 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A macrolide antibiotic isolated from Streptomyces sp. An antiangiogenic (IC₅₀ = 0.8 nM) agent. Bacterial and eukaryal threonyl-tRNA synthetase (THrRS) inhibitor. Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and induction of apoptosis. Also acts as a CDK inhibitor.
Shipping Conditions
gel pack
Storage Conditions
-20 ̊C
Shelf Life
36 months

Alternative Products

CatalogName
254805Borrelidin
207093-01Borrelidin (Treponemycin, U 78548, C2989)
MBS651415-01Borrelidin (Treponemycin, Antibiotic U 78548, Antibiotic C2989)
TBI1399-1MGBorrelidin, Threonyl-tRNA synthase inhibitor; Angiogenesis inhibitor

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