Tipifarnib, Free base

CAT: 0026-2296-1Size: 1 mgDry Ice: NoHazardous: No
CAT#:0026-2296-1Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent, selective, nonpeptidomimetic inhibitor of farnesyl protein transferase (FPT), an enzyme involved in protein processing (farnesylation) for signal transduction. Displays significant antitumor effects in vivo.  Tipifarnib competitively inhibits the farnesylation of lamin B (IC₅₀ = 0.86 nM) and K-RasB (IC₅₀ = 7.9 nM) peptide substrates and inhibits the cell growth of ~75% of a panel of 53 human tumor cell lines tested.
Shipping Conditions
gel pack
Storage Conditions
-20 ̊C
Shelf Life
36 months

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