Products for Research Use Only

PKC412

CAT: 0026-2052-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-2052-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cell-permeable. A derivative of Staurosporine (Cat. No. 1048) that inhibits a variety of serine/threonine and tyrosine kinases including protein kinase C (PKC) IC₅₀ = 50 nM), cyclic AMP-dependent protein kinase (PKA) (IC₅₀ = 2.4 µM), S6 kinase (IC₅₀ = 5.0 µM), and EGFR (IC₅₀ = 3.0 µM). PKC412 reverses the efflux function of the multidrug resistance (MDR)-1 gene product, P-glycoprotein (P-gp).
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
24 months