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Epothilone B

CAT: 0026-2012-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-2012-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A macrolide anticancer agent. Similar to paclitaxel (Cat. No. 1567-25), epothilone B induces microtubule polymerization and stabilizes microtubules against depolymerization conditions. In addition to promoting tubulin polymerization and stabilization of microtubules, this agent is cytotoxic for cells overexpressing P-glycoprotein, a characteristic that distinguishes it from the taxanes. Also induces G2-M cell cycle arrest (EC₅₀= 3 - 92 nM).
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
24months

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